Table 2.
The minimum inhibitory concentration (MIC) of different antifungal drugs used to treat S. boydii and S. aurantiacum planktonic cells and biofilms.
| Fungi | Antifungal drugs (range 128–0.125 μg/ml) | MIC of planktonic cells (μg/ml) | MIC of biofilms (μg/ml) |
|---|---|---|---|
| Scedosporium (Pseudallescheria) | Caspofungin | 64 | 32 |
| boydii CBS 120157 | Fluconazole | 32 | >128 |
| Itraconazole | 2 | >128 | |
| Voriconazole | 1 | >128 | |
| Scedosporium (Pseudallescheria) | Caspofungin | 64 | 32 |
| boydii CBS 117410 | Fluconazole | 64 | >128 |
| Itraconazole | 2 | >128 | |
| Voriconazole | 0.5 | >128 | |
| Scedosporium aurantiacum CBS | Caspofungin | 64 | 32 |
| 136046 | Fluconazole | 16 | >128 |
| Itraconazole | 1 | >128 | |
| Voriconazole | 0.5 | >128 | |
| Scedosporium aurantiacum CBS | Caspofungin | 64 | 32 |
| 136047 | Fluconazole | 32 | >128 |
| Itraconazole | 1 | >128 | |
| Voriconazole | 0.5 | >128 |
An antifungal susceptibility test was performed using planktonic cells and pre-formed biofilms.