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. 2016 Dec 22;56(9):1045–1055. doi: 10.1007/s40262-016-0492-2

Fig. 4.

Fig. 4

Pharmacokinetic trough level at steady state following a dose of 30 IU/kg rAHF-PFM and BAY 81-8973; a solid line indicates that a switch from rAHF-PFM to BAY 81-8973 leads to an expected increase in trough levels for this patient; a dashed line indicates a decrease in trough level following a switch to BAY 81-8973. C trough trough level, rAHF-PFM antihemophilic factor (recombinant) plasma/albumin-free method