. 2016 Dec 22;56(9):1045–1055. doi: 10.1007/s40262-016-0492-2

Table 6.

Dosing required to maintain FVIII plasma levels >1 IU/dL (simulation of 1000 patients)

Dosing frequency	BAY 81-8973		rAHF-PFM		Ratio^a
Dosing frequency	Dose for 50% of patients to maintain >1 IU/dL, IU/kg	Absolute dose per year for 70-kg patient, IU	Dose for 50% of patients to maintain >1 IU/dL, IU/kg	Absolute dose per year for 70-kg patient, IU	Ratio^a
2×/week	52.4	381,472	161	1,172,080	0.33
3×/week	14.4	157,248	39.1	426,972	0.37

FVIII factor VIII, rAHF-PFM antihemophilic factor (recombinant) plasma/albumin-free method

^aRatio of BAY 81-8973:rAHF-PFM