Table 3. Ethanol-induced excitation of midbrain DA neurons from adult drinkers.

Values presented are percent change in firing rate in response to 10, 20, and 50 mM EtOH ±SEM. Two tailed t-tests were used to compare the properties of VTA DA neurons from naïve and experienced mice; p < 0.05 was considered significant.

	Naïve (n = 7)	EtOH (n = 11)	p value
Baseline FR	2.5 ± 0.3	2.8 ± 0.4	0.6
ISI CV	0.13 ± 0.03	0.25 ± 0.06	0.15
10 mM	−3.0 ± 3.1	7.7 ± 5.6	0.17
20 mM	−2.7 ± 3.3	5.2 ± 5.8	0.32
50 mM	1.9 ± 4.4	18.0 ± 12.5	0.33