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. Author manuscript; available in PMC: 2018 Sep 1.
Published in final edited form as: Neuropharmacology. 2017 Jun 21;123:420–432. doi: 10.1016/j.neuropharm.2017.06.019

Table 2. Deltorphin II effects by VTA cell type measured in current clamp.

Firing rate was analyzed in neurons firing spontaneously, and membrane potential was analyzed in quiescent neurons. Changes from baseline were determined statistically as described in the Methods.

Cell type Inhibited No change Excited
All cells 43% (113/264) 36% (96/264) 21% (55/264)
TH(+)* 33% (13/39) 56% (22/39) 10% (4/39)
Ih(+)TH(−) 33% (9/27) 33% (9/27) 33% (9/27)
Ih(−) 54% (13/24) 21% (5/24) 25% (6/24)
*

Distribution of response types was statistically different between dopamine (TH(+)) neurons and non-dopamine (Ih(+)TH(−) and Ih(−)) neurons, 2 × 3 Freeman-Halton extension of the Fisher Exact Test, p = 0.01.