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. Author manuscript; available in PMC: 2017 Aug 21.
Published in final edited form as: Clin Trials. 2015 Oct 22;13(2):169–179. doi: 10.1177/1740774515609106

Figure 1.

Figure 1

Estimated α level of the test for interaction based on the Tmax and χ12 statistics of STEPP survival endpoints: Kaplan-Meier (K-M) and Hazard Ratio (HRO-E) based on O − E estimation.

The 99% interval for permutation probability value 0.01, 0.05 and 0.10 are (0.00, 0.02), (0.04, 0.06) and (0.08, 0.12), respectively.

Events represents the average proportion of observed events.

Subpops. represents the average number of subpopulations.

The results were based on 300 simulations of sample size N.