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. 2017 Aug 21;3:17051. doi: 10.1038/cddiscovery.2017.51

Figure 8.

Figure 8

FPND prevented any atorvastatin-related decrease in zebrafish locomotion activity in a dose-dependent manner. In all, 1 dpf zebrafish were treated with or without FPND for 3 h, and then incubated with 2 μM atorvastatin for 3 days. The swimming distances of fishes were examined by the Viewpoint Zebrabox system (Viewpoint, Paris, France) and the total distance moved in 10 min was calculated. Representative patterns of zebrafish locomotion traced from different treatment groups. Statistical analysis of the total distance traveled by each zebrafish larva in the different treatment groups (12 fish larval per group from three independent experiments). The results show the mean distance traveled by 36 larvae and are expressed in mm/10 min. Data presented in the bar graphs are the mean±S.D. of three independent experiments.