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. Author manuscript; available in PMC: 2017 Sep 1.
Published in final edited form as: Cytokine. 2017 Jun 16;97:108–116. doi: 10.1016/j.cyto.2017.06.002

Fig. 7.

Fig. 7

Kaplan-Meyer and histological analysis of wildtype and Ccr2−/− neonatal mice challenged with E. coli. (A) Wildtype C57BL/6NJ (WT) and Ccr2−/− mice were given 2.8 × 106 CFUs of E. coli. WT mice had significantly better survival at 3 days post-E. coli challenge compared to Ccr2−/− mice (p = 0.0089) (n = 24 for WT neonates and n = 24 for Ccr2−/− neonates). (B) Representative examples of lungs from Ccr2−/− and WT neonatal mice at 24, 48, and 72 h post-E. coli or PBS challenge. (10× magnification, arrows point to focal areas of inflammatory cell accumulation).