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. 2016 Feb 22;32(2):127–136. doi: 10.1007/s12264-016-0015-z

Fig. 4.

Fig. 4

The density of c-Fos-positive cells in the NAcSh was significantly higher in TLR4 −/− than in WT mice after performing novelty-seeking behavior. A. Representative photomicrographs showing c-Fos-positive cells in the BLA, mPFCv, NAcSh, and PVT of WT (n = 5) and TLR4 −/− (n = 3) mice. B. Histograms quantifying the density of c-Fos-positive cells in the BLA, mPFCv, NAcSh, and PVT of WT and TLR4 −/− mice. BLA, basolateral amygdala; mPFCv, ventral medial prefrontal cortex; NAcSh, nucleus accumbens shell; PVT, paraventricular thalamic nucleus. Scale bar, 100 μm. **P < 0.01.