Effects of Aβ31–35 and HNG on expression levels of caspase-3 and STAT3 mRNA in rat hippocampus. A, Histogram showing that the Aβ31–35-induced increase in caspase-3 mRNA was suppressed by HNG, and this was blocked by genistein, a tyrosine kinase inhibitor. B, Histogram showing that the Aβ31–35-induced inhibition of STAT3 mRNA was reversed by HNG, and this was also blocked by genistein. Each column represents the mean ± SEM (**P < 0.01).