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. 2016 May 9;32(6):523–530. doi: 10.1007/s12264-016-0031-z

Fig. 2.

Fig. 2

Agmatine decreased glutamate release and increased glutamate uptake of hippocampal synaptosomes from chronic morphine-treated rats. A Effect of agmatine on glutamate release in chronic morphine-treated rats. B Effect of agmatine on the uptake of [3H]-glutamate in synaptosomes from chronic morphine-treated rats (n = 9; *P < 0.05 vs Con group, # P < 0.05 vs Mor group, one-way ANOVA followed by Bonferroni test). Con control, Mor morphine, Agm agmatine, Agm + Mor agmatine administered with morphine for 5 days.