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. 2016 Sep 10;32(6):538–544. doi: 10.1007/s12264-016-0059-0

Table 2.

Treatment outcomes, methadone doses, and methadone blood levels.

(n = 76)
Treatment outcomes
Drop-outs during weeks 4–12, % (n) 9.2 (7)
Retention, days 81.6 ± 8.9
Longest continuous period of negative urine tests, weeks 8.0 ± 3.9
No. of negative urine samples 8.7 ± 3.5
Methadone doses and blood levels
Average dose weeks 4–12, mg 46.8 ± 24.3
Mean dose at blood sampling, mg 50.9 ± 25.3
Total trough, ng/mL 222.0 ± 132.3
Free trough, ng/mL 11.6 ± 7.3
Total peak, ng/mL 356.2 ± 203.7
Free peak, ng/mL 18.8 ± 11.4
Free peak to free trough ratio, % 1.716 ± 0.553
Total peak to total trough ratio, % 1.766 ± 0.636