Treatment outcomes
|
|
Drop-outs during weeks 4–12, % (n) |
9.2 (7) |
Retention, days |
81.6 ± 8.9 |
Longest continuous period of negative urine tests, weeks |
8.0 ± 3.9 |
No. of negative urine samples |
8.7 ± 3.5 |
Methadone doses and blood levels
|
|
Average dose weeks 4–12, mg |
46.8 ± 24.3 |
Mean dose at blood sampling, mg |
50.9 ± 25.3 |
Total trough, ng/mL |
222.0 ± 132.3 |
Free trough, ng/mL |
11.6 ± 7.3 |
Total peak, ng/mL |
356.2 ± 203.7 |
Free peak, ng/mL |
18.8 ± 11.4 |
Free peak to free trough ratio, % |
1.716 ± 0.553 |
Total peak to total trough ratio, % |
1.766 ± 0.636 |