. 2016 Sep 10;32(6):538–544. doi: 10.1007/s12264-016-0059-0

Table 3.

Relationship between methadone plasma blood level and treatment outcome during weeks 4–12 after 4 weeks of stabilization on methadone maintenance treatment.

Variable (n = 76)	Retention, parameter vector, B (95% CI)	Longest continuous period (weeks) of negative urine tests, parameter vector, B (95% CI)	Total number of negative urine tests, parameter vector, B (95% CI)
Free peak^a	−0.022 (−0.128, 0.084)	0.002 (−0.043, 0.048)	−0.003 (−0.045, 0.039)
Free trough^a	0.301 (−0.049, 0.661)	0.147 (−0.007, 0.301)	0.129 (−0.012, 0.270)
Total peak^a	−0.017 (−0.112, 0.078)	0.008 (−0.033, 0.049)	0.003 (−0.034, 0.041)
Total trough^a	−0.040 (−0.134, 0.054)	0.005 (−0.036, 0.046)	0.001 (−0.037, 0.038)
Average dose	0.001 (−0.084, 0.087)	0.033 (−0.003, 0.070)	0.027 (−0.006, 0.060)

No results were significantly different.

^aAdjusted by dose on day of blood sampling.