Table 2.
GR regulated TFs in column A (interaction from) and the targeted downstream RAGS in column B (interaction to)
| Interaction from | Interaction to | Interaction effect | Interaction type | Organisms |
|---|---|---|---|---|
| c-Rel (NF-κB subunit) | c-Myb | + | TR | Homo;Mus;Rattus |
| c-Rel (NF-κB subunit) | STAT1 | u | TR | Homo;Mus;Rattus |
| c-Rel (NF-κB subunit) | STAT5A | u | TR | Homo;Mus;Rattus |
| c-Rel (NF-κB subunit) | IL-6 | + | TR | Homo;Mus;Rattus |
| C/EBPα | RNF12 | u | TR | Homo;Mus;Rattus |
| C/EBPα | c-Fos | + | TR | Homo;Mus;Rattus |
| C/EBPβ | STAT6 | + | B | Homo;Mus;Rattus |
| C/EBPβ | b-Myb | u | TR | Homo;Mus;Rattus |
| C/EBPβ | LTBP2 | u | TR | Homo;Mus;Rattus |
| C/EBPβ | HNF1-α | + | B | Homo;Mus;Rattus |
| C/EBPβ | HNF1-β | + | B | Homo;Mus;Rattus |
| C/EBPβ | PAX2 | u | TR | Homo;Mus;Rattus |
| C/EBPβ | c-Jun | + | B | Homo;Mus;Rattus |
| C/EBPβ | Ghrelin | u | TR | Homo;Mus;Rattus |
| C/EBPβ | IL-6 | + | TR | Homo;Mus;Rattus |
| C/EBPβ | c-Fos | + | TR | Homo;Mus;Rattus |
| c-Jun/c-Fos | c-Fos | u | TR | Homo;Mus;Rattus |
| COUP-TFII | HNF1-β | + | TR | Homo;Mus;Rattus |
| E2A | ZNF143 | u | TR | Homo;Mus;Rattus |
| E2A | c-Fos | u | TR | Homo;Mus;Rattus |
| GCR-α | STAT5A | + | B | Homo;Mus;Rattus |
| GCR-α | TBP | + | B | Homo;Mus;Rattus |
| GCR-α | STAT6 | - | B | Homo;Mus;Rattus |
| GCR-α | c-Jun/c-Fos | - | B | Homo;Mus;Rattus |
| GCR-α | SMAD3 | - | B | Homo;Mus;Rattus |
| GCR-α | IL-6 | - | TR | Homo;Mus;Rattus |
| GCR-α | ZNF167 | u | TR | Homo;Mus;Rattus |
| HIF1A | IL-6 | + | TR | Homo;Mus;Rattus |
| HIF1A | SMAD3 | + | B | Homo;Mus;Rattus |
| HIF1A | Mxi1 | + | TR | Homo;Mus;Rattus |
| HIF1A | RNF183 | u | TR | Homo;Mus;Rattus |
| HIF1A | c-Jun | + | B | Homo;Mus;Rattus |
| HIF1A | Junctin | + | TR | Homo;Mus;Rattus |
| IRF1 | RNF168 | u | TR | Homo;Mus |
| IRF1 | c-Myb | - | TR | Homo;Mus;Rattus |
| IRF1 | RNF12 | u | TR | Homo;Mus;Rattus |
| IRF1 | c-Jun | + | B | Homo;Mus;Rattus |
| NF-AT2(NFATC1) | LTBP3 | + | TR | Homo;Mus;Rattus |
| NF-κB | PAX2 | u | TR | Homo;Mus;Rattus |
| NF-κB | PTBP1 | u | TR | Homo;Mus;Rattus |
| NF-κB | FosB | u | TR | Homo;Mus;Rattus |
| NF-κB | JunB | u | TR | Homo;Mus;Rattus |
| NF-κB | Ghrelin | u | TR | Homo;Mus;Rattus |
| NF-κB | Junctin | u | TR | Homo;Mus;Rattus |
| NF-κB | STAT5A | u | TR | Homo;Mus;Rattus |
| NF-κB | IL-6 | + | TR | Homo;Mus;Rattus |
| NF-κB | SMAD3 | + | B | Homo;Mus;Rattus |
| NF-κB1 (p50) | c-Fos | - | B | Homo;Mus;Rattus |
| NF-κB1 (p50) | c-Myb | + | TR | Homo;Mus;Rattus |
| NF-κB1 (p50) | JunB | u | TR | Homo;Mus;Rattus |
| NF-κB1 (p50) | IL-6 | + | TR | Homo;Mus;Rattus |
| NF-κB1 (p50) | FosB | u | TR | Homo;Mus;Rattus |
| NF-κB1 (p50) | c-Jun | - | B | Homo;Mus;Rattus |
| Oct1 | JunD | u | TR | Homo;Mus;Rattus |
| Oct1 | IL-6 | u | TR | Homo;Mus;Rattus |
| Oct1 | FosB | u | TR | Homo;Mus;Rattus |
| Oct1 | STAT4 | u | TR | Homo;Mus;Rattus |
| Oct1 | LTBP3 | u | TR | Homo;Mus;Rattus |
| Oct1 | HNF1-β | u | TR | Homo;Mus;Rattus |
| Oct1 | HNF1-α | + | B | Homo;Mus;Rattus |
| p53 | RNF10 | u | TR | Homo;Mus;Rattus |
| p53 | STAT4 | u | TR | Homo;Mus;Rattus |
| p53 | b-Myb | - | B | Homo;Mus;Rattus |
| p53 | TBP | - | B | Homo;Mus;Rattus |
| p53 | A-Myb | u | TR | Homo;Mus;Rattus |
| p53 | c-Myb | - | B | Homo;Mus;Rattus |
| p53 | Large T antigen (SV40) | + | B | Homo;Mus;Rattus |
| p53 | STAT5A | - | Unspecified | Homo;Mus;Rattus |
| p53 | c-Fos | u | TR | Homo;Mus;Rattus |
| p53 | IL-6 | - | TR | Homo;Mus;Rattus |
| p73 | ZNF143 | + | B | Homo;Mus;Rattus |
| p73 | STAT1 | + | TR | Homo;Mus;Rattus |
| PIT1 | c-Fos | + | TR | Homo;Mus;Rattus |
| PPAR-γ | SMAD3 | - | B | Homo;Mus;Rattus |
| RelA (p65 NF-κB subunit) | STAT6 | u | TR | Homo;Mus;Rattus |
| RelA (p65 NF-κB subunit) | RhoA | + | TR | Homo;Mus;Rattus |
| RelA (p65 NF-κB subunit) | JunB | + | TR | Homo;Mus;Rattus |
| RelA (p65 NF-κB subunit) | STAT5A | + | TR | Homo;Mus;Rattus |
| RelA (p65 NF-κB subunit) | FosB | + | TR | Homo;Mus;Rattus |
| RelA (p65 NF-κB subunit) | IL-6 | + | TR | Homo;Mus;Rattus |
| RelA (p65 NF-κB subunit) | ZNF143 | u | TR | Homo;Mus;Rattus |
| SMAD3 | c-Jun | + | TR | Homo;Mus;Rattus |
| SMAD3 | LTBP3 | + | TR | Homo;Mus;Rattus |
| SMAD3 | JunB | + | TR | Homo;Mus;Rattus |
| SMAD3 | c-Jun/c-Fos | + | B | Homo;Mus;Rattus |
| STAT3 | ZNF148 | - | B | Homo;Mus;Rattus |
| STAT3 | STAT1 | u | TR | Homo;Mus;Rattus |
| STAT3 | IL-6 | + | TR | Homo;Mus;Rattus |
| STAT3 | JunB | + | TR | Homo;Mus;Rattus |
| STAT3 | LTBP3 | u | TR | Homo;Mus;Rattus |
| STAT3 | STAT2 | u | TR | Homo;Mus;Rattus |
| STAT3 | c-Fos | + | TR | Homo;Mus;Rattus |
| STAT5 | c-Fos | + | TR | Homo;Mus;Rattus |
| STAT5 | STAT1 | - | C | Homo;Mus;Rattus |
| STAT5A | c-Fos | + | TR | Homo;Mus;Rattus |
| STAT5B | STAT1 | - | C | Homo;Mus;Rattus |
| STAT6 | STAT1 | - | C | Homo;Mus;Rattus |
| STAT6 | RhoA | + | TR | Homo;Mus;Rattus |
| T-bet | STAT1 | + | TR | Homo;Mus;Rattus |
| T-bet | SETBP1 | + | TR | Homo;Mus;Rattus |
The effect of the interaction on target gene expression is shown in column C, and the type of interaction is in column D. The organism this interaction was reported in is listed in column E. + indicates activation; - indicates inhibition; u indicates unspecified interaction. TR indicates transcription regulation; B indicates binding; C indicates competition. Homo: Home sapiens, Mus: Mus musculus; Rattus: Rattus norvegicus.