TABLE 1.

IDILI classification, daily dose, C_max, and references from which C_max values were taken

Drug	IDILI Liability	Cmax	Daily Dose	Cmax Reference
		μM	mg
Aspirin	IDILI−	47	1300	Brandon et al., 1986
Azithromycin	IDILI−	0.5	500	Xu et al., 2008
Buspirone	IDILI−	0.005	15	Xu et al., 2008
Idarubicin	IDILI−	0.02	1	Xu et al., 2008
Levofloxacin	IDILI−	15.7	500	Xu et al., 2008
Moxifloxacin	IDILI−	6.2	400	Stass et al., 1998
Pioglitazone	IDILI−	2.67	15	Xu et al., 2008
Promethazine	IDILI−	0.06	25	Xu et al., 2008
Rofecoxib	IDILI−	1	12.5	Gottesdiener et al., 2003
Sertraline	IDILI−	0.06	50	Xu et al., 2008
Bromfenac	IDILI+	13.5	50	Gumbhir-Shah et al., 1997
Chlorpromazine	IDILI+	0.84	200	Xu et al., 2008
Clavulanate	IDILI+	12	125	Hu et al., 2002
Diclofenac	IDILI+	7.44	100	Xu et al., 2008
Doxorubicin	IDILI+	1	1	Barpe et al., 2010
Flucloxacillin	IDILI+	72.6	250	Røder et al., 1995
Flutamide	IDILI+	0.36	750	Xu et al., 2008
Ibuprofen	IDILI+	164	800	Bramlage and Goldis, 2008
Isoniazid	IDILI+	77	300	Xu et al., 2008
Naproxen	IDILI+	300	500	Setiawati et al., 2009
Nimesulide	IDILI+	21.08	200	Xu et al., 2008
Telithromycin	IDILI+	2.77	800	Xu et al., 2008
Trovafloxacin	IDILI+	5	300	Xu et al., 2008
Valproic acid	IDILI+	175	60	Rha et al., 1993

IDILI classification was determined by a set of criteria described in Xu et al. (2008). IDILI− indicates that the drug is not associated with IDILI, whereas IDILI+ indicates that the drug is associated with IDILI.