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. 2017 Jun 1;117(1):89–101. doi: 10.1038/bjc.2017.156

Figure 1.

Figure 1

miRNA expression in breast cancer cells and post-wound invasion of breast cancer cells following treatment with miRNA mimics monitored by the ECIS system. (A) Differential expression of miRNAs in breast cancer cells was quantified using the Megaplex TaqMan MicroRNA Arrays v2.0 and Megaplex Primer Pools following the manufacturer’s instructions. Small RNA U48 was used to normalise the expression data. (B) post-wound invasion of breast cancer cells. Cells were transfected in an ECIS plate with miRNA mimics and negative controls (25 nM each), respectively. The electric wound was performed at 25 h and 36 h (2600 μA for 20 s). The signal of impedance was continuously recorded in the ECIS system. *P<0.05. A full colour version of this figure is available at the British Journal of Cancer journal online.