Table 2. Expression of miR-7, miR-221-5p and miR-339-5p in Human Breast Cancer.

	miR-7					miR-221-5p					miR-339-5p
Patients	N	Mean	s.d.	s.e.	P-value	N	Mean	s.d.	s.e.	P-value	N	Mean	s.d.	s.e.	P-value
Normal	15	87.90	141.10	36.40		20	73.30	114.10	25.50		22	73.80	105.20	22.40
Tumour	66	57.89	67.39	8.29		80	56.73	62.08	6.94		80	43.45	49.18	5.50
NPI1	34	69.60	82.70	14.20		38	66.00	78.40	12.70		39	51.20	62.80	10.10
NPI2	18	54.10	56.60	13.30		26	51.57	48.08	9.43		25	38.89	35.57	7.11
NPI3	12	35.68	15.10	4.36	0.028 vs NPI1	14	45.50	29.93	8.00		13	33.79	21.06	5.84
Grade1	11	74.10	93.40	28.10		12	71.50	93.30	26.90		12	56.20	75.40	21.80
Grade2	14	91.30	94.20	25.20	0.0106 vs Grade3	21	83.40	77.00	16.80	0.028 vs Grade3	22	63.00	61.00	13.00	0.026 vs Grade3
Grade3	40	41.66	40.36	6.38	0.0382 vs Grade1	46	40.59	36.64	5.40		44	30.63	27.53	4.15
TNM1	30	76.40	86.80	15.90		39	72.90	77.90	12.50		39	57.36	62.33	9.98
TNM2	26	47.23	47.06	9.23		28	45.46	43.85	8.29	0.086 vs TNM3	28	33.20	32.04	6.05	0.043 vs TNM1
TNM3	6	29.96	4.44	1.81		7	30.54	3.30	1.25	0.0017 vs TNM1	6	22.38	2.03	0.83	0.0012 vs TNM1
TNM4	2	29.43	1.21	0.86		2	29.42	1.42	1.01		3	23.65	3.75	2.16	0.0021 vs TNM1
Alive&Well	48	64.10	77.30	11.20		58	59.75	70.18	9.21		59	45.97	55.57	7.23
With distant metastasis	4	44.03	16.68	8.34		5	39.33	12.25	5.48		5	29.59	10.52	4.71
With local recurrence	3	46.00	20.50	11.90		3	47.70	20.80	12.00		3	35.82	15.99	9.23
Died of breast cancer	8	32.63	12.75	4.51		11	50.30	38.80	11.70		10	37.71	27.90	8.82
With incidence (incl. local recurrence)	15	38.35	15.55	4.01	0.034 vs Alive and Well	19	46.99	30.68	7.04		18	35.14	21.94	5.17
With metastasis and death	12	36.43	14.52	4.19	0.024 vs Alive and well	16	46.85	32.74	8.19		15	35	23.4	6.04

Abbreviations: NPI=Nottingham Prognostic Index (1: <3.4 (good prognosis); 2: 3.4–5.4 (moderate prognosis); 3: >5.4 (poor prognosis)); TNM=tnm classification of malignant tumours.