Figure 2.

Pan-genome of human-associated Methanomassiliicoccales. (a) Core, variable and unique gene families in the pan-genome of the human-associated Methanomassiliicoccales. Between brackets, the number of unique gene families and the percentage they represent within each genome. The number of unique genes and its percentage are also given for the pan-genome of ‘Ca. Mmc. intestinalis’ as the three genomes of this species are very close. Mint, ‘Ca. Mmc. intestinalis’ Malv, ‘Ca. Mmp. alvus’ Mlum, Mmc. luminyensis. (b) Rarefaction analysis of gene family discovery in the pan-genome of human-associated Methanomassiliicoccales, determined on the basis of identity percentage (dark green) and KO annotation (light green).