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. Author manuscript; available in PMC: 2018 Jul 6.
Published in final edited form as: Nature. 2017 Jun 28;547(7661):55–60. doi: 10.1038/nature22992

Extended Data Figure 3. Bi-allelic hits for TBC1D12 and LEPROTL1 promoter mutations.

Extended Data Figure 3

a, Sequencing read alignment for tumour BDD-162 shows location of TBC1D12 hotspot mutations on mutually exclusive alleles. b, Location of hotspot mutations near the LEPROTL1 transcription start on mutually exclusive sequencing reads in patient BDD-MEX-BR-116. Reference bases are indicated in grey, mismatched bases in their respective colours (A, green; C, blue; G, orange; T, red). Hotspot mutation sites are outlined with black boxes. Images generated with the Integrative Genomics Viewer70.