Manual dosing images (top panels) indicate a substantial fraction of the dose falling outside the body (extracorporeal), posteroinferior to the pelvis, mostly in the midline gluteal folds in addition to a fraction within the colonic lumen. The intrarectal dosing images (bottom panels) indicate all visible signals within the colonic lumen within the pelvis. Fused SPECT and CT images (left panels) indicate bone in amber scale with lumbosacral spine, pelvis, and humerus (top to bottom); color in images indicate radiolabel intensity. Right panels are maximum intensity projections of SPECT image (color scale signal intensity) at similar angle of rotation without bony landmarks; labels indicate intraluminal and extracorporeal radiolabel. SPECT, single-photon emission computed tomography; CT, transmission computed tomography.