FIG. 2.

Peak and set point VLs in Groups 1 and 2 compared to historical SIVmac239-infected macaques. (A) Log-transformed peak and set point VLs in r04132 and r07032 were plotted alongside the same VL values from Mamu-B*08⁺ rhesus macaques that were rectally infected with SIVmac239 as part of ongoing and recent studies conducted in our laboratory (Martins et al., unpublished observations).^32,33,39 Each symbol corresponds to one monkey. For this analysis, unvaccinated macaques (n = 12) are denoted by open circles, whereas vaccinated monkeys (n = 16) are denoted by open triangles. (B) Peak and set point VLs in r08019 and r01049 are displayed alongside VLs from SIVmac239-infected, Mamu-A*01⁺ rhesus macaques. As in A, open circles correspond to unvaccinated monkeys (n = 8), whereas open triangles indicate vaccinated animals (n = 8). In all cases, set point was determined as the geometric mean of VLs measured between week 6 PI and the last available postinfection time point. Bars correspond to medians.