Table 2. Clinical uses of sedation drugs.

	Midazolam	Propofol	Ketamine	Dexmedetomidine
Dose	0.5-1 mg over 2 min (0.01-0.1 mg/kg)	- Loading dose 0.5 mg/kg and 0.5 mg/kg every 3-5 min	0.25-0.5 mg/kg	Loading dose 0.5-1 µg/kg during 10 min and infusion
		- Infusion: 25-75 µg/kg/min		0.1-1 µg/kg/h
Onset time	2-3 min	9-51 sec (average: 30 sec)	30 sec	5-10 min
Duration	60-120 min	3-10 min	5-10 min	60-120 min