Table 2.
Enriched pathways of NL and BS proteins revealed by DAVID analysis. Proteins identified from each tissue set were compared to the genome of Gallus gallus to determine if there is enrichment for proteins from certain pathways, using DAVID program. Score of >1.3 is significant. The top 5 enriched pathways suggest a highly metabolic mileu.
| Nucleus Laminaris (NL) | Dorsal Brainstem (BS) | ||||
|---|---|---|---|---|---|
|
| |||||
| Cluster | Enrichment Score | Cluster | Enrichment Score | ||
| 1 | Mitochondrial | 16.28 | 1 | Mitochondrial | 12.50 |
| 2 | Ribosomal/Translation | 13.98 | 2 | Metabolic | 12.24 |
| 3 | Protein folding | 9.94 | 3 | Ribosomal/Translation | 9.48 |
| 4 | Cytoskeletal | 9.18 | 4 | Respiration | 7.49 |
| 5 | Metabolic | 9.08 | 5 | Oxidative | 7.29 |
| 6 | Protein transport | 8.79 | 6 | Protein folding | 6.39 |
| 7 | Cellular respiration | 8.21 | 7 | Nucleotide binding | 5.95 |
| 8 | Nucleotide binding | 7.37 | 8 | Cytoskeletal | 5.89 |
| 9 | Neuronal projection | 7.12 | 9 | Nucleotide binding | 5.09 |
| 10 | RNA recognition | 6.69 | 10 | Oxidoreductase | 4.97 |