Table 6. Grading of recommendations.

Recommendation Grade	Definition	Transcription
Class I	The recommendation’s level of evidence (A) and benefits are clear; utilization at clinical sites is high.	(Is recommended)
Class Iia	The recommendation’s level of evidence (B) and benefits are credible; utilization at clinical sites is high or moderate.	(Should be considered)
Class Iib	The recommendation’s level of evidence (C or D) and benefits are not credible, but utilization at clinical sites is high or moderate.	(May be considered)
Class III	The recommendation’s level of evidence (C or D) and benefits are not credible with the risk of harmful results; utilization at clinical sites is low.	(Is not recommended)