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. Author manuscript; available in PMC: 2017 Aug 21.
Published in final edited form as: Cell Rep. 2017 May 30;19(9):1858–1873. doi: 10.1016/j.celrep.2017.05.014

Figure 2. IDH1 promotes GBM progression in vivo.

Figure 2

(A–C) Cell proliferation in GIC-20 expressing shScramble or shIDH1, GIC-387 with pLKO or shIDH1, and in NSCs with stable overexpression of IDH1 (n=3; Mean ± SD).

(D–I) Quantification of bioluminescence of intracranial engraftment models, using GIC-20 expressing pLKO and shIDH1, GIC-387 with shScramble and shIDH1, and NSCs expressing CSII and CSII-IDH1 (n=7–10; Mean ± SEM); and the corresponding Kaplan-Meier survival curves (n=9–10).

* p<0.005; ** p<0.05; *** p<0.01; **** p<0.0005; # p<0.001; ## p<0.0001. See also Figure S2.