Table I.
TRPV1 coexpresses with Whirlin isoforms in sensory neurons.
| WT | Whirlinneo/neo | Whirler | |
|---|---|---|---|
| TRPV1+ | 33 ± 1 | 31 ± 1 | 34 ± 1 |
| TRPV1+ × IB4+ | 4 ± 1 | 6 ± 1 | 4 ± 1 |
| TRPV1+ × CGRP+ | 50 ± 4 | 49 ± 3 | 40 ± 4 |
| TRPV1+ × NF200+ | 11 ± 1 | 11 ± 2 | 11 ± 3 |
| TRPV1+ × Whirlin+ | 64 ± 3 | 63 ± 4 | 49 ± 8 |
| Whirlin+ | 56 ± 1 | 51 ± 2 | 53 ± 1 |
| Whirlin+ × IB4+ | 35 ± 2 | 35 ± 3 | 43 ± 5 |
| Whirlin+ × CGRP+ | 43 ± 2 | 49 ± 6 | 53 ± 5 |
| Whirlin+ × NF200+ | 41 ± 3 | 42 ± 4 | 31 ± 5 |
| Whirlin+ × TRPV1+ | 40 ± 2 | 40 ± 3 | 31 ± 7 |
Immunohistochemistry was carried out on serial DRGs cryo-sections of 14 μm from wild type, whirler and whirlinneo/neo mice. Immunohistochemical staining was performed with polyclonal antibodies for TRPV1, Whirlin and the neuronal markers CGRP, IB4 and NF200. Data expressed mean ± SEM as percentage of total neurons analyzed per each section. Three animals and a minimum of 5 sections per group were analyzed.