Table 1.
Heart Rate (beats/min) | Fractional Shortening (%) | Ejection Fraction (%) | Diastolic LVID (mm) | Diastolic LV Vol (μl) | LVPW (mm) | Peak Percentage (%) | |
---|---|---|---|---|---|---|---|
GRK2fl/fl Sham | 519 ± 17 | 33.38 ± 1.99 | 62.31 ± 2.70 | 3.87 ± 0.13 | 66.12 ± 5.34 | 1.23 ± 0.04 | −18.37 ± 1.04 |
GRK2fl/fl I/R | 505 ± 12 | 22.75 ± 1.23* | 45.63 ± 2.20* | 4.34 ± 0.11† | 86.92 ± 5.63† | 0.98 ± 0.04* | −12.84 ± 0.81* |
GRK2fl/fl I/R Gal | 506 ± 20 | 34.09 ± 2.83‡ | 62.64 ± 3.81‡ | 3.85 ± 0.14§ | 65.27 ± 4.95§ | 1.21 ± 0.04|| | −17.83 ± 1.13|| |
Values are mean ± SEM.
p < 0.001 vs. sham.
p < 0.05 vs. sham.
p < 0.001 vs. I/R vehicle.
p < 0.05 vs. I/R vehicle.
p < 0.01 vs. I/R vehicle.
Gal = gallein; I/R = ischemia-reperfusion; LVID = left ventricular internal dimension; LVPW = left ventricle posterior wall thickness; LV Vol = left ventricular volume.