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. Author manuscript; available in PMC: 2018 Aug 30.
Published in final edited form as: Behav Brain Res. 2017 Jun 27;333:161–170. doi: 10.1016/j.bbr.2017.06.045

Figure 5. The reinforcing effects of optogenetic ICSS of LDTg inputs to the VTA require the activation of D1 and D2 DA receptors in the NAcc shell.

Figure 5

Results are illustrated as described in Figure 4. Relative to saline (blue lines), reinforced lever pressing was significantly reduced from 9–30 (C; SCH23390) and 10–30 minutes (D; Raclopride) of the test session (p’s<0.05–0.01). E. Left. Bilateral NAcc shell injection sites for the 7 ChR2 rats tested (blue dots). E. Right. Representative cresyl violet-stained section showing a NAcc shell injection site.