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. Author manuscript; available in PMC: 2017 Aug 21.
Published in final edited form as: Cell Rep. 2017 Jun 20;19(12):2490–2502. doi: 10.1016/j.celrep.2017.05.072

Figure 6. Erythroid gene occupancy by LDB1 and CTCF is common.

Figure 6

(A) Genes are considered in two groups: erythroid genes and other genes. For each group the percent of genes whose promoters are occupied by LDB1, CTCF, both proteins or neither protein is plotted. Each group is considered as a whole (all) and the group whose expression is reduced upon LDB1 KD and rescued by expression of full length LDB1 in MEL cells is considered separately (KD/rescued). (B) Models depicting long range interaction between an LDB1-bound enhancer and a CTCF or LDB1 occupied gene to activate expression.