Figure 2.

Mesoscopic measures plotted against radiophenomic modules.

(a) Necrosis-related module: Median ± 2 SD of CBV in FLAIR hyperintensity is higher in minor necrosis than in pronounced necrosis, p_corr = 0.0003.

(b) Median ± 2 SD of vessel size in FLAIR hyperintensity is higher and has a larger variance in minor necrosis, p_corr = 0.2.

(c) Edema-related module: Median ± 2 SD of CBV in ipsilateral normal-appearing matter (NAM) outside of T2/FLAIR hyperintense tumor is lower in edema than in infiltration, p_corr = 0.039.

(d) Proliferation-related module: Median ± 2 SD of axial diffusivity ipsilateral normal-appearing matter (NAM) outside of T2/FLAIR hyperintense tumor is lower in moderate to severe mass effect than in mild or no mass effect, p_corr = 0.048.

CBV: cerebral blood volume; FLAIR: fluid-attenuated inversion recovery.