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. 2017 Mar 29;42(9):1871–1883. doi: 10.1038/npp.2017.41

Figure 2.

Figure 2

Effects of R-MOD and JJC8-016 on basal and cocaine-enhanced locomotor activity. (a) Pretreatment with R-MOD did not significantly alter cocaine-enhanced locomotor activity. (b) Pretreatment with JJC8-016 dose-dependently attenuated cocaine-induced increase in locomotion. (c) R-MOD alone dose-dependently increased locomotor activity. (d) JJC8-016 did not significantly alter basal level of locomotor behavior. Within-subjects design, n=8 in each treatment. *P<0.05, **p<0.01, and ***p<0.001 compared with vehicle control.