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. Author manuscript; available in PMC: 2018 Aug 1.
Published in final edited form as: Drug Alcohol Depend. 2017 Jun 3;177:268–276. doi: 10.1016/j.drugalcdep.2017.03.035

Figure 2.

Figure 2

Pre- to post-treatment change in regions of interest activity during reward anticipation correlated with percent days of abstinence during treatment, for A2 win in the (A) medial prefrontal cortex (MPFC), (B) left insula and (C) left nucleus accumbens (NAc), and (D) for A2 loss in the left NAc. Black circles indicate adolescents who received contingency management (CM) for abstinence and patch compliance, gray circles received CM for patch compliance alone; closed circles received nicotine patch, open circles received placebo patch.