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Histamine Pharmacodynamic Parameters by Group.
| Group 1 | Group 2 | Group3* | |
|---|---|---|---|
| AUEC | 4,654 ± 2,997 | 4,233 ± 1,819 | 8,702 ± 2,776* |
| EffmaxNt | 127 ± 52 | 136 ± 33 | 198 ± 53* |
| Tmax | 9±6 | 10 ± 6 | 18± 7* |
Comparisons of area under the effect curve (AUEC) in flux units × minutes, maximal effect over baseline (EffmaxNt) in flux, and time to maximal effect over baseline (Tmax) in minutes between Groups 1, 2, and 3.
Mean ± standard deviation values for each response group,
P < .01.
