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. Author manuscript; available in PMC: 2018 Sep 1.
Published in final edited form as: Neurobiol Aging. 2017 Jun 6;57:153–161. doi: 10.1016/j.neurobiolaging.2017.05.023

Table 2.

Year 10 and change values in cognition and neuroimaging measures.

Outcome Year 10 Score Δ Year 10 to Year13 (SE)
Mean (SD) Estimate (SE) P value
Hippocampus
 Volume (cm3)    9.57 (1.14)   −0.60 (0.08) <.001
 Mean diffusivity (10−3 mm2/s)    1.33 (0.01)       0.08 (0.004) <.001
Global brain measures
 GM volume (cm3) 532.19 (53.19) −24.61 (1.86) <.001
 GM mean diffusivity (10−3 mm2/s)    1.10 (0.52)       0.03 (0.003) <.001
 WM fractional anisotropy    0.36 (0.01)   −0.0008 (0.0006) .142
 WM radial diffusivity (10−3 mm2/s)    0.70 (0.33)      0.007 (0.002) <.001
 WM axial diffusivity (10−3 mm2/s)    1.12 (0.03)      0.009 (0.002) <.001
 WM hyperintensities1    5.51 (7.11)      3.59 (0.47) <.001
Cognition
 Modified Mini-Mental State   93.65 (6.38) −0.85 (0.44) .054
 Examination

Notes. GM = gray matter. SE = standard error of the mean. WM = white matter.

1

Log-transformed.