Table 5.
Fully Adjusted Linear Regression Models Estimating the Effects of Nerve Amplitude on Resting Heart Rate (n=1,729)
Poor Motor Nerve Amplitude, <1 mV Model R2=0.10 |
Continuous Motor Nerve Amplitude, Effect per Standard Deviation Slower Model R2=0.10 |
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Independent Variable | Beta Estimate | Standard Error | P-Value | Independent Variable | Beta Estimate | Standard Error | P-Value |
Poor Motor Nerve Amplitude <1 mV | 2.3 | 0.8 | 0.003 | Motor Amplitude, per SD Lower2 | 0.9 | 0.1 | <0.001 |
Age1, Per Year Older | 0.1 | 0.1 | 0.4 | Age1, Per Year Older | 0.1 | 0.1 | 0.5 |
Women | 1.4 | 0.5 | 0.005 | Women | 1.5 | 0.5 | 0.002 |
Black Race | 0.4 | 0.5 | 0.5 | Black Race | 0.5 | 0.5 | 0.3 |
Pittsburgh Site | −1.7 | 0.5 | <0.001 | Pittsburgh Site | −1.7 | 0.5 | <0.001 |
Diabetes Status | Diabetes Status | ||||||
Diabetes | 2.6 | 0.6 | <0.001 | Diabetes | 2.6 | 0.6 | <0.001 |
Impaired Fasting Glucose | 1.8 | 0.7 | 0.006 | Impaired Fasting Glucose | 2.0 | 0.7 | 0.003 |
Beta Blocker Use | −4.9 | 0.6 | <0.001 | Beta Blocker Use | −5.0 | 0.6 | <0.001 |
Tricyclic Antidepressant Use | 4.1 | 1.6 | 0.01 | Tricyclic Antidepressant Use | 4.3 | 1.6 | 0.008 |
IL-6 (Ln) | 1.5 | 0.4 | <0.001 | IL-6 (Ln) | 1.5 | 0.4 | <0.001 |
CRP (Ln) | 0.7 | 0.2 | 0.001 | CRP (Ln) | 0.7 | 0.2 | 0.001 |
Fasting Cholesterol (per SD higher) | 0.8 | 0.3 | 0.002 | Fasting Cholesterol (per SD higher) | 0.8 | 0.3 | <0.001 |
Age centered at age 76 years
Amplitude, mV, mean ± SD = 3.3 ± 2.0