Table 2.

GEE results with subcortical volumes as dependent variables and factors age, sex, neuroimaging site, Intracranial volume (ICV), childhood adversity (CTQ), MDD diagnosis and interactions.

Source	Wald Chi-square	df	p-value
Neuroimaging site	513.9	7	<0.001
Hemisphere	281.6	1	<0.001
ICV	1458.5	1	<0.001
Age	1317.2	1	<0.001
MDD diagnosis	0.89	1	0.35
Sex	4.0	1	0.045
Region	27478.5	6	<0.001
CTQ	0.3	1	0.61
Diagnosis × Sex	0.05	1	0.83
CTQ × Sex	4.4	1	0.036
Diagnosis × Region	6.0	6	0.43
Diagnosis × CTQ	5.4	1	0.02
CTQ × Region	37.1	6	<0.001
Sex × Region	72.8	6	<0.001
Diagnosis × Sex × Region	6.5	6	0.37
Diagnosis × Sex × CTQ	0.65	1	0.42
Sex × CTQ × Region	19.6	6	0.003
Diagnosis × Region × CTQ	14.1	6	0.028
Diagnosis × Sex × Region × CTQ	13.5	6	0.035