Table 2. Rank-order correlations of intraepithelial lymphocytes with immunological factors in ESCC.

	High CD3i	High CD8i	Diffuse CD3i	Diffuse CD8i	High PD1i	High PD-L1+ TILs	PD-L1 high
	>20 CD3+ TILs/100 TCs	>13 CD8+ TILs/100 TCs			>6 PD-1+ TILs/100 TCs		>10% PD-L1+ TCs
High CD3i
>20 CD3+ TILs/100 TCs	x	r = 0.642	r = 0.595	r = 0.392	r = 0.456	r = 0.091	r = 0.348
		p < 0.001	p < 0.001	p < 0.001	p < 0.001	p = 0.409	p < 0.001
High CD8i
>13 CD8+ TILs/100 TCs		x	r = 0.419	r = 0.591	r = 0.442	r = 0.093	r = 0.265
			p < 0.001	p < 0.001	p < 0.001	p = 0.533	p = 0.005
Diffuse CD3i
			x	r = 0.385	r = 0.326	r = 0.09	r = 0.363
				p < 0.001	p < 0.001	p = 0.072	p < 0.001
Diffuse CD8i
				x	r = 0.265	r = 0.056	r = 0.269
					p = 0.014	p = 0.533	p = 0.003
High PD1i
>6 PD-1+ TILs/100 TCs					x	r = 0.193	r = 0.170
						p = 0.04	p = 0.081
High PD-L1+ TILs
						x	r = 0.152
							p = 0.1