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. 2017 Jan 31;8(29):46915–46927. doi: 10.18632/oncotarget.14911

Figure 6. Combinational treatment of Vandetanib and GDC-0941 leads to profound inhibition of STAT3 and PI3K/AKT activation.

Figure 6

In Daoy, MEB-Med-8A, D283 Med and D341 Med cells were treated with 2 μM of Vandetanib for 48h alone or in combination with 1 μM of GDC-0941 respectively. Total protein levels and phosphorylation status of AKT and STAT3 were determined by Western blot. GAPDH served as loading control.