Table 1. Baseline characteristics of patients with BRCA1/2 mutation advanced recurrent ovarian cancer treated with olaparib.
Baseline Criteria | N (%) | |
---|---|---|
Study subjects | 108 | |
Age, Year Median (Range) | 55 (38-79) | |
Tumor type | High grade serous | 83 (77%) |
Endometrioid | 8 (7.4%) | |
Others | 9 (8.2%) | |
Unknown | 8 (7.4%) | |
Stage at diagnosis | 1 | 1 (0.9%) |
2 | 10 (9.3%) | |
3 | 76 (70.3%) | |
4 | 11 (10.2%) | |
Unknown | 10 (9.3%) | |
Optimally debulked? | Yes | 58 (53.7%) |
No | 20 (18.5%) | |
Unknown | 30 (27.8%) | |
BRCA1/2 mutation | BRCA1 | 78 (79%) |
BRCA2 | 30 (21%) | |
Past Medical History of Breast Cancer | Yes | 40 (38%) |
No | 68 (62%) | |
Previous breast cancer chemotherapy | Yes | 20 (18.5%) |
No | 88 (81.5%) | |
Platinum status at enrolment to Olaparib | Platinum-Sensitive | 65 (60.1%) |
Platinum-Resistant | 38 (35.2%) | |
Unknown | 5 (4.7%) |