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. 2017 May 3;8(29):47195–47205. doi: 10.18632/oncotarget.17587

Figure 1. PBK expression is up-regulated in HCC and associated with poor outcomes.

Figure 1

(A) The expression of PBK mRNA in 56 pairs of HCC specimens was determined by qRT-PCR. (B) PBK protein level was evaluated in 16 HCC cases by western blot. The representative images (left panel) and the statistics (right panel) were presented. (C) PBK expression was examined 520 paired HCC and nontumorous tissues and 96 paired HCC and metastatic tissues by immunohistochemistry (IHC). The IHC score of PBK was shown and compared. (D, E) Kaplan-Meier analyses was conducted to assess the value of PBK in overall and disease-free survivals of patients with HCC in our and TCGA cohorts.