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. 2017 May 3;8(29):47195–47205. doi: 10.18632/oncotarget.17587

Figure 5. PBK is transcriptionally regulated by FoxM1.

Figure 5

(A) The correlation of PBK and FoxM1 mRNA expression was determined in 423 cases in TCGA cohort (left panel) and 56 cases in our cohort (right panel). (B) The representative images of PBK and FoxM1 IHC staining were presented (top panel). The correlation between PBK and FoxM1 expression in 520 HCC tissues was determined and shown (bottom panel). (C) Luciferase assays were performed to effect of FoxM1 overexpression or knockdown on the activity of PBK promoter in Bel-7404 cells. (D) The effect of FoxM1 overexpression or knockdown on PBK expression was determined in HCC cells. All *P < 0.05, **P < 0.01.