Table 1. Correlation of clinicopathological features and PBK expression.
| Variable | PBK expression | |||
|---|---|---|---|---|
| All cases | Low expression | High expression | P valuea | |
| Age (years)b | 0.830 | |||
| < 49 | 239 | 106 (44.4%) | 133 (55.6%) | |
| ≥ 49 | 281 | 122 (43.4%) | 159 (56.6%) | |
| Gender | 0.003 | |||
| Male | 470 | 196 (41.7%) | 274 (58.3%) | |
| Female | 50 | 32 (64.0 %) | 18 (36.0%) | |
| HBsAg | 0.214 | |||
| Positive | 80 | 30 (37.5%) | 50 (62.5%) | |
| Negative | 440 | 198 (45.0%) | 242 (55.0%) | |
| AFP (ng/ml) | 0.523 | |||
| < 20 | 123 | 57 (46.3%) | 66 (53.7%) | |
| ≥ 20 | 397 | 171 (43.1%) | 226 (56.9%) | |
| Cirrhosis | 0.326 | |||
| Yes | 433 | 194 (44.8%) | 239 (55.2%) | |
| No | 87 | 34 (39.1%) | 53 (60.9%) | |
| Tumor size (cm) | 0.001 | |||
| < 5 | 112 | 64 (57.1%) | 48 (42.9%) | |
| ≥ 5 | 408 | 164 (40.2%) | 224 (59.8%) | |
| Tumor multiplicity | 0.355 | |||
| Single | 326 | 148 (45.4%) | 178 (54.6%) | |
| Multiple | 194 | 80 (41.2%) | 114 (58.8%) | |
| Tumor Differentiation | 0.535 | |||
| Well-Moderate | 376 | 168 (44.7%) | 208 (55.3%) | |
| Poor-undifferentiated | 144 | 60 (41.7%) | 84 (58.3%) | |
| TNM | 0.107 | |||
| I–II | 278 | 131 (47.1%) | 147 (52.9%) | |
| III–IV | 242 | 97 (40.1%) | 145 (59.9%) | |
| Vascular invasion | 0.003 | |||
| Yes | 111 | 35 (47.2%) | 76(52.8%) | |
| No | 409 | 193 (31.5%) | 216 (68.5%) | |
| Tumor Capsule | 0.302 | |||
| Absent | 296 | 124 (41.9%) | 172 (58.1%) | |
| Present | 224 | 104 (46.4%) | 120 (53.6%) | |
| LNM | 0.019 | |||
| No | 487 | 220 (45.2%) | 267 (54.8) | |
| Yes | 33 | 8 (24.7%) | 25 (75.8%) | |
aChi-square test; bMedian age; AFP, alpha-fetoprotein; HBV, hepatitis B virus; LNM, lymph node metastasis.