Table 2. Down-deregulation numbers of the 14 frequently hypermethylated genes in 16 CRC samples compared with their paired adjacent normal tissues from TCGA.
| Gene Symble | Hypermethylation frequency | Down-regulated samples | Gene Symble | Hypermethylation frequency | Down-regulated samples |
|---|---|---|---|---|---|
| ADHFE1 | 98.13% | 16 | CNRIP1 | 97.76% | 15 |
| TMEFF2 | 95.52% | 16 | ZNF134 | 96.27% | 15 |
| IRF4 | 99.63% | 16 | PHOX2A | 97.01% | 15 |
| ZNF132 | 97.01% | 16 | FLI1 | 97.01% | 15 |
| NSG1 | 96.27% | 16 | NTRK3 | 97.76% | 15 |
| NELL1 | 97.01% | 16 | KCNQ5 | 98.51% | 15 |
| SLC6A15 | 95.15% | 15 | GPM6A | 97.76% | 15 |