Table 2. Association between microRNA-binding site polymorphisms in IL13 gene and the risk of colorectal cancer.
| Genotypes | Cases | Controls | ORadjusted (95% CI) | P-value |
|---|---|---|---|---|
| No.(%) | No.(%) | |||
| rs847 A>G | ||||
| GG | 247 (48.15) | 277 (48.09) | 1.00 | |
| AG | 231 (45.03) | 246 (42.71) | 0.69 (0.42–1.14) | 0.15 |
| AA | 31 (6.04) | 49 (8.51) | 1.03 (0.80–1.33) | 0.84 |
| Dominant model | 0.97 (0.76–1.25) | 0.83 | ||
| Recessive model | 0.68 (0.42–1.11) | 0.12 | ||
| rs848 T>G | ||||
| GG | 247 (48.15) | 278 (48.26) | 1.00 | |
| GT | 227 (44.25) | 240 (41.67) | 1.03 (0.79–1.33) | 0.84 |
| TT | 35 (6.82) | 49 (8.50) | 0.78 (0.48–1.26) | 0.31 |
| Dominant model | 0.99 (0.77–1.27) | 0.93 | ||
| Recessive model | 0.77 (0.48–1.23) | 0.27 | ||
| rs1295685 C>T | ||||
| CC | 245 (47.76) | 272 (47.22) | 1.00 | |
| CT | 225 (43.86) | 238 (41.32) | 1.02 (0.79–1.32) | 0.87 |
| TT | 31 (6.04) | 53 (9.20) | 0.63 (0.39–1.04) | 0.07 |
| Dominant model | 0.96 (0.75–1.22) | 0.72 | ||
| Recessive model | 0.63 (0.39–1.01) | 0.06 |
ORadjusted: adjusted for BMI, occupation, and age