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. 2017 May 7;8(29):47412–47424. doi: 10.18632/oncotarget.17658

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Copyright: © 2017 Liu et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License 3.0 (CC BY 3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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(A, B) The expression levels of Yap and CTGF (a Yap target) were downregulated by SB204741 at the protein (A) and mRNA levels (B). (C) 5-HT induced the entry of Yap into the nucleus, and the inhibition of 5-HT_2BR led to the retention of Yap in the cytoplasm and inactivation of Yap. **P < 0.01.