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. 2017 May 10;8(29):47586–47594. doi: 10.18632/oncotarget.17739

Figure 1. Pro-fibrogenic stimuli activates MRTF-A expression post-transcriptionally.

Figure 1

(A, B) Liver fibrosis was induced in C57/BL6 mice by CCl4 injection. Hepatic MRTF-A expression was evaluated by qPCR (A) and Western (B). (C, D) Liver fibrosis was induced in C57/BL6 mice by TAA injection. Hepatic MRTF-A expression was evaluated by qPCR (C) and Western (D). (E, F) Liver fibrosis was induced in C57/BL6 mice by bile duct ligation (BDL). Hepatic MRTF-A expression was evaluated by qPCR (E) and Western (F). (G, H) HSC-T6 cells were treated with TGF-β or PDGF-BB for 24 hours. MRTF-A expression was evaluated by qPCR (G) and Western (H).