Table 1. Clinicopathologic characteristics of the Mannheim cohort (n=84): High risk versus low risk MIBCs according to FOXM1 expression.
| Total | % | High Risk | % | Low Risk | % | p-values | |
|---|---|---|---|---|---|---|---|
| Cohort Characteristics | |||||||
| Cohort size | 84 | 54 | (64) | 30 | (36) | ||
| median age | 66 | 66 | 64 | 0.685 | |||
| female | 20 | (24) | 14 | (26) | 6 | (20) | 0.603 |
| male | 64 | (76) | 40 | (74) | 24 | (80) | |
| Progress (n=76) | 43 | (57) | 29 | (62) | 14 | (33) | 0.182 |
| TNM Staging | |||||||
| pT1 | 1 | (1) | 0 | (0) | 1 | (3) | 0.34 |
| pT2 | 21 | (25) | 16 | (30) | 5 | (17) | |
| pT3 | 47 | (56) | 29 | (54) | 18 | (60) | |
| pT4 | 15 | (18) | 9 | (17) | 6 | (20) | |
| pN+ (n=82) | 31 | (38) | 18 | (35) | 13 | (43) | 0.483 |
| cM+ (n=70) | 7 | (10) | 6 | (14) | 1 | (4) | 0.236 |
| Grading | |||||||
| G2 | 17 | (20) | 8 | (15) | 9 | (30) | 0.086 |
| G3 | 67 | (80) | 46 | (85) | 21 | (70) | |
| Additional Therapy (n=81) | |||||||
| NAC | 1 | (1) | 1 | (2) | 0 | (0) | 1.0 |
| AC | 11 | (14) | 7 | (14) | 4 | (14) | 0.607 |