Table 2. Relationship between NDRG1 and clinicopathologic variables.
Variable | Case | NDRG1 expression | P value | |
---|---|---|---|---|
Positive | Negative | |||
n=97 | n=57 | n=40 | ||
Age (years) | 0.520 | |||
≤65 | 52 | 29 | 23 | |
>65 | 45 | 28 | 17 | |
Gender | 0.119 | |||
Male | 72 | 39 | 33 | |
Female | 25 | 18 | 7 | |
ECOG performance | 0.183 | |||
0 | 68 | 37 | 31 | |
1 | 29 | 20 | 9 | |
Tumor size (cm) | 0.001 | |||
≤4 ×3 | 52 | 39 | 13 | |
>4 ×3 | 45 | 18 | 27 | |
Location from anal verge | 0.290 | |||
0-5cm | 52 | 28 | 24 | |
5-10cm | 45 | 29 | 16 | |
Local invasion | 0.002 | |||
T2 | 26 | 22 | 4 | |
T3+T4 | 71 | 35 | 36 | |
Lymphatic invasion | 0.005 | |||
N0 | 27 | 22 | 5 | |
N1+N2 | 70 | 35 | 35 | |
TNM stage | 0.005 | |||
II | 27 | 22 | 5 | |
III | 70 | 35 | 35 |
The staging results were determined by two independent pathologists according to the 7th edition of the AJCC Cancer Staging system.