Table 1. Expression of HIF-2α and VM and the relation with the clinicopathologic features in pancreatic carcinoma.
Variables | HIF-2α | VM | |||||
---|---|---|---|---|---|---|---|
No. | Positive | Negative | P-value | Positive | Negative | P-value | |
Gender | 0.306 | 0.473 | |||||
Male | 42 | 26 | 16 | 20 | 22 | ||
Female | 28 | 21 | 7 | 16 | 12 | ||
Age (years) | 1.000 | 0.467 | |||||
≤ 65 | 41 | 28 | 13 | 23 | 18 | ||
>65 | 29 | 19 | 10 | 13 | 16 | ||
Tumor location | 0.569 | 0.278 | |||||
Head | 52 | 36 | 16 | 29 | 23 | ||
Body and tail | 18 | 11 | 7 | 7 | 11 | ||
Tumor size (cm) | 0.122 | 0.147 | |||||
≤2 | 27 | 15 | 12 | 17 | 10 | ||
>2 | 43 | 32 | 11 | 19 | 24 | ||
Differentiation | 0.026 | 0.014 | |||||
Well | 8 | 3 | 5 | 2 | 6 | ||
Moderate | 17 | 9 | 8 | 5 | 12 | ||
Poor | 45 | 35 | 10 | 29 | 16 | ||
Clinical stage | 0.017 | 0.001 | |||||
I | 25 | 12 | 13 | 6 | 19 | ||
II | 45 | 35 | 10 | 30 | 15 | ||
Lymph node metastasis | |||||||
Yes | 38 | 30 | 8 | 0.040 | 25 | 13 | 0.016 |
No | 32 | 17 | 15 | 11 | 21 |