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. 2017 May 18;8(29):47816–47830. doi: 10.18632/oncotarget.18001

Table 1. Baseline demographics and clinical characteristics of patients.

Variable LGG (grade I/II) HGG (grade III/IV) P value
Patients N=28 N=92 -
Gendera
 Male 46.4% (13/28) 57.6% (53/92) 0.298
 Female 53.6% (15/28) 42.3% (39/92)
Ageb
 Mean±SD 35.9±16.2 49.3±15.0 <0.001*
Locationc
 Supratentorial 10.7%(3/28) 1.1%(1/92) 0.060
 Subtentorial 89.3%(25/28) 98.9%(91/92)
Histologic feature
 Diffuse astrocytoma 39.3%(11/28) - -
 Oligodendroglioma 7.1%(2/28) - -
 Oligoastrocytoma 39.3%(11/28) - -
 Anaplastic astrocytoma - 6.5%(6/92) -
 Anaplastic oligodendroglioma - 5.4%(5/92) -
 Anaplastic oligoastrocytoma - 19.6%(18/92) -
 Glioblastoma - 67.4%(62/92) NA
 Miscellaneous 14.3%(4/28) 1.1%(1/92) NA

Note: Difference between LGG and HGG patients was evaluated with the Pearson Chi-Squarea, unpaired Student t testb and continuity correctionc. * The difference between the LGG and HGG groups was significant.